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References Section
Eicosapentaenoic Acid (EPA) References for 2000:
Zuijdgeest-Van Leeuwen, S. D., P. C. Dagnelie, et al. (2000).
"Eicosapentaenoic acid ethyl ester supplementation in cachectic cancer patients
and healthy subjects: effects on lipolysis and lipid oxidation." Clin Nutr
19(6): 417-23.
Ziboh, V. A., C. C. Miller, et al. (2000). "Metabolism of polyunsaturated fatty
acids by skin epidermal enzymes: generation of antiinflammatory and
antiproliferative metabolites." Am J Clin Nutr 71(1 Suppl):
361S-6S.
Zeleniuch-Jacquotte, A., V. Chajes, et al. (2000). "Reliability of fatty acid
composition in human serum phospholipids." Eur J Clin Nutr 54(5):
367-72.
Yu, R., A. Yamada, et al. (2000). "Production of eicosapentaenoic acid by a
recombinant marine cyanobacterium, Synechococcus sp." Lipids 35(10):
1061-4.
Youdim, K. A., A. Martin, et al. (2000). "Essential fatty acids and the brain:
possible health implications." Int J Dev Neurosci 18(4-5): 383-99.
Yorioka, N., T. Masaki, et al. (2000). "Lipid-lowering therapy and coagulation/fibrinolysis
parameters in patients on peritoneal dialysis." Int J Artif Organs 23(1):
27-32.
Yaqoob, P., H. S. Pala, et al. (2000). "Encapsulated fish oil enriched in alpha-tocopherol
alters plasma phospholipid and mononuclear cell fatty acid compositions but not
mononuclear cell functions." Eur J Clin Invest 30(3): 260-74.
Yano, M., E. Kishida, et al. (2000). "Docosahexaenoic acid and vitamin E can
reduce human monocytic U937 cell apoptosis induced by tumor necrosis factor."
J Nutr 130(5): 1095-101.
Xiao, Y. F., S. N. Wright, et al. (2000). "Coexpression with beta(1)-subunit
modifies the kinetics and fatty acid block of hH1(alpha) Na(+) channels." Am
J Physiol Heart Circ Physiol 279(1): H35-46.
Woods, R. K., F. C. Thien, et al. (2000). "Dietary marine fatty acids (fish oil)
for asthma." Cochrane Database Syst Rev(2): CD001283.
Woods, R. K., F. C. Thien, et al. (2000). "Dietary marine fatty acids (fish oil)
for asthma." Cochrane Database Syst Rev(4): CD001283.
Wirth, M., F. Kirschbaum, et al. (2000). "Chemical and biochemical composition
of caviar from different sturgeon species and origins." Nahrung 44(4):
233-7.
Wigmore, S. J., M. D. Barber, et al. (2000). "Effect of oral eicosapentaenoic
acid on weight loss in patients with pancreatic cancer." Nutr Cancer
36(2): 177-84.
Westphal, S., M. Orth, et al. (2000). "Postprandial chylomicrons and VLDLs in
severe hypertriacylglycerolemia are lowered more effectively than are
chylomicron remnants after treatment with n-3 fatty acids." Am J Clin Nutr
71(4): 914-20.
Weber, P. and D. Raederstorff (2000). "Triglyceride-lowering effect of omega-3
LC-polyunsaturated fatty acids--a review." Nutr Metab Cardiovasc Dis
10(1): 28-37.
Webb, Y., L. Hermida-Matsumoto, et al. (2000). "Inhibition of protein
palmitoylation, raft localization, and T cell signaling by 2-bromopalmitate and
polyunsaturated fatty acids." J Biol Chem 275(1): 261-70.
Watkins, B. A., Y. Li, et al. (2000). "Dietary ratio of (n-6)/(n-3)
polyunsaturated fatty acids alters the fatty acid composition of bone
compartments and biomarkers of bone formation in rats." J Nutr 130(9):
2274-84.
Watanabe, S., K. Katagiri, et al. (2000). "Dietary docosahexaenoic acid but not
eicosapentaenoic acid suppresses lipopolysaccharide-induced interleukin-1 beta
mRNA induction in mouse spleen leukocytes." Prostaglandins Leukot Essent
Fatty Acids 62(3): 147-52.
Wang, L., Y. Shimizu, et al. (2000). "Comparison of the fatty acid composition
of total lipids and phospholipids in breast milk from Japanese women."
Pediatr Int 42(1): 14-20.
Wander, R. C. and S. H. Du (2000). "Oxidation of plasma proteins is not
increased after supplementation with eicosapentaenoic and docosahexaenoic
acids." Am J Clin Nutr 72(3): 731-7.
Wallace, J. M., A. J. McCabe, et al. (2000). "Bioavailability of n-3
polyunsaturated fatty acids (PUFA) in foods enriched with microencapsulated fish
oil." Ann Nutr Metab 44(4): 157-62.
Volker, D. H., P. E. FitzGerald, et al. (2000). "The eicosapentaenoic to
docosahexaenoic acid ratio of diets affects the pathogenesis of arthritis in
Lew/SSN rats." J Nutr 130(3): 559-65.
Volker, D., P. Fitzgerald, et al. (2000). "Efficacy of fish oil concentrate in
the treatment of rheumatoid arthritis." J Rheumatol 27(10):
2343-6.
Vermunt, S. H., R. P. Mensink, et al. (2000). "Effects of dietary
alpha-linolenic acid on the conversion and oxidation of 13C-alpha-linolenic
acid." Lipids 35(2): 137-42.
Valk, E. E. and G. Hornstra (2000). "Relationship between vitamin E requirement
and polyunsaturated fatty acid intake in man: a review." Int J Vitam Nutr Res
70(2): 31-42.
Tsuge, H., N. Hotta, et al. (2000). "Effects of vitamin B-6 on (n-3)
polyunsaturated fatty acid metabolism." J Nutr 130(2S Suppl):
333S-334S.
Totland, G. K., L. Madsen, et al. (2000). "Proliferation of mitochondria and
gene expression of carnitine palmitoyltransferase and fatty acyl-CoA oxidase in
rat skeletal muscle, heart and liver by hypolipidemic fatty acids." Biol Cell
92(5): 317-29.
Torres, I. C., L. Mira, et al. (2000). "Study of the effects of dietary fish
intake on serum lipids and lipoproteins in two populations with different
dietary habits." Br J Nutr 83(4): 371-9.
Tomobe, Y. I., K. Morizawa, et al. (2000). "Dietary docosahexaenoic acid
suppresses inflammation and immunoresponses in contact hypersensitivity reaction
in mice." Lipids 35(1): 61-9.
Tisdale, M. J. (2000). "Metabolic abnormalities in cachexia and anorexia."
Nutrition 16(10): 1013-4.
Takahashi, Y. and T. Ide (2000). "Dietary n-3 fatty acids affect mRNA level of
brown adipose tissue uncoupling protein 1, and white adipose tissue leptin and
glucose transporter 4 in the rat." Br J Nutr 84(2): 175-84.
Stredansky, M., E. Conti, et al. (2000). "Production of polyunsaturated fatty
acids by Pythium ultimum in solid-state cultivation." Enzyme Microb Technol
26(2-4): 304-307.
Stone, N. J. (2000). "The Gruppo Italiano per lo Studio della Sopravvivenza
nell'Infarto Miocardio (GISSI)-Prevenzione Trial on fish oil and vitamin E
supplementation in myocardial infarction survivors." Curr Cardiol Rep
2(5): 445-51.
Stene, L. C., J. Ulriksen, et al. (2000). "Use of cod liver oil during pregnancy
associated with lower risk of Type I diabetes in the offspring." Diabetologia
43(9): 1093-8.
Stark, K. D., E. J. Park, et al. (2000). "Effect of a fish-oil concentrate on
serum lipids in postmenopausal women receiving and not receiving hormone
replacement therapy in a placebo-controlled, double-blind trial." Am J Clin
Nutr 72(2): 389-94.
Stalenhoef, A. F., J. de Graaf, et al. (2000). "The effect of concentrated n-3
fatty acids versus gemfibrozil on plasma lipoproteins, low density lipoprotein
heterogeneity and oxidizability in patients with hypertriglyceridemia."
Atherosclerosis 153(1): 129-38.
Soriguer, F. J., F. J. Tinahones, et al. (2000). "Varying incorporation of fatty
acids into phospholipids from muscle, adipose and pancreatic exocrine tissues
and thymocytes in adult rats fed with diets rich in different fatty acids."
Eur J Epidemiol 16(6): 585-94.
Solvoll, K., E. Soyland, et al. (2000). "Dietary habits among patients with
atopic dermatitis." Eur J Clin Nutr 54(2): 93-7.
Smit, E. N., M. Koopmann, et al. (2000). "Effect of supplementation of
arachidonic acid (AA) or a combination of AA plus docosahexaenoic acid on
breastmilk fatty acid composition." Prostaglandins Leukot Essent Fatty Acids
62(6): 335-40.
Sinclair, A. J., K. J. Murphy, et al. (2000). "Marine lipids: overview "news
insights and lipid composition of Lyprinol"." Allerg Immunol (Paris)
32(7): 261-71.
Simopoulos, A. P. (2000). "Human requirement for N-3 polyunsaturated fatty
acids." Poult Sci 79(7): 961-70.
Serhan, C. N., T. Takano, et al. (2000). "Formation of endogenous
"antiinflammatory" lipid mediators by transcellular biosynthesis. Lipoxins and
aspirin-triggered lipoxins inhibit neutrophil recruitment and vascular
permeability." Am J Respir Crit Care Med 161(2 Pt 2): S95-S101.
Serhan, C. N., C. B. Clish, et al. (2000). "Novel functional sets of
lipid-derived mediators with antiinflammatory actions generated from omega-3
fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and
transcellular processing." J Exp Med 192(8): 1197-204.
Sebedio, J. L., S. H. Vermunt, et al. (2000). "The effect of dietary trans
alpha-linolenic acid on plasma lipids and platelet fatty acid composition: the
TransLinE study." Eur J Clin Nutr 54(2): 104-13.
Schwartz, J. (2000). "Role of polyunsaturated fatty acids in lung disease."
Am J Clin Nutr 71(1 Suppl): 393S-6S.
Schmitz, P. G., K. Zhang, et al. (2000). "Eicosapentaenoic acid suppresses
PDGF-induced DNA synthesis in rat mesangial cells: involvement of thromboxane
A2." Kidney Int 57(3): 1041-51.
Sauer, L. A., R. T. Dauchy, et al. (2000). "Mechanism for the antitumor and
anticachectic effects of n-3 fatty acids." Cancer Res 60(18):
5289-95.
Sane, S., M. Baba, et al. (2000). "Eicosapentaenoic acid reduces pulmonary edema
in endotoxemic rats." J Surg Res 93(1): 21-7.
Sametz, W., M. Jeschek, et al. (2000). "Influence of polyunsaturated fatty acids
on vasoconstrictions induced by 8-iso-PGF(2alpha) and 8-iso-PGE(2)."
Pharmacology 60(3): 155-60.
Salem, M. L., K. Kishihara, et al. (2000). "N-3 polyunsaturated fatty acids
accentuate B16 melanoma growth and metastasis through suppression of tumoricidal
function of T cells and macrophages." Anticancer Res 20(5A):
3195-203.
Sakamoto, N., T. Nishiike, et al. (2000). "Effects of eicosapentaenoic acid
intake on plasma fibrinolytic and coagulation activity by using physical load in
the young." Nutrition 16(1): 11-4.
Sakamoto, N., S. Yoshimoto, et al. (2000). "Changes of HDL subfractions by
eicosapentaenoic acid intake and physical load in 20- to 25-year-old men."
Ann Nutr Metab 44(3): 115-20.
Rosella, O., A. Sinclair, et al. (2000). "Polyunsaturated fatty acids reduce
non-receptor-mediated transcellular permeation of protein across a model of
intestinal epithelium in vitro." J Gastroenterol Hepatol 15(6):
626-31.
Rose, F., L. Kiss, et al. (2000). "E. coli hemolysin-induced lipid mediator
metabolism in alveolar macrophages: impact of eicosapentaenoic acid." Am J
Physiol Lung Cell Mol Physiol 279(1): L100-9.
Romero, N., P. Robert, et al. (2000). "[Fatty acids composition and proximate of
7 fish species of Isla de Pascua]." Arch Latinoam Nutr 50(3):
304-8.
Rissanen, T., S. Voutilainen, et al. (2000). "Fish oil-derived fatty acids,
docosahexaenoic acid and docosapentaenoic acid, and the risk of acute coronary
events: the Kuopio ischaemic heart disease risk factor study." Circulation
102(22): 2677-9.
Richardson, A. J., T. Easton, et al. (2000). "Red cell and plasma fatty acid
changes accompanying symptom remission in a patient with schizophrenia treated
with eicosapentaenoic acid." Eur Neuropsychopharmacol 10(3):
189-93.
Retterstol, K., A. M. Lund, et al. (2000). "Metabolism of some radiolabeled
essential fatty acids in isolated rat hepatocytes is affected by dietary
ethanol." Alcohol 21(1): 19-26.
Refsgaard, H. H., P. M. Brockhoff, et al. (2000). "Free polyunsaturated fatty
acids cause taste deterioration of salmon during frozen storage." J Agric
Food Chem 48(8): 3280-5.
Reddy, P. S., T. C. Kumar, et al. (2000). "Differential formation of
octadecadienoic acid and octadecatrienoic acid products in control and
injured/infected potato tubers." Biochim Biophys Acta 1483(2):
294-300.
Ravichandran, D., A. Cooper, et al. (2000). "Effect of
1-(gamma)linolenyl-3-eicosapentaenoyl propane diol on the growth of human
pancreatic carcinoma in vitro and in vivo." Eur J Cancer 36(3):
423-7.
Puri, B. K., A. J. Richardson, et al. (2000). "Eicosapentaenoic acid treatment
in schizophrenia associated with symptom remission, normalisation of blood fatty
acids, reduced neuronal membrane phospholipid turnover and structural brain
changes." Int J Clin Pract 54(1): 57-63.
Petrik, M. B., M. F. McEntee, et al. (2000). "Antagonism of arachidonic acid is
linked to the antitumorigenic effect of dietary eicosapentaenoic acid in
Apc(Min/+) mice." J Nutr 130(5): 1153-8.
Petrik, M. B., M. F. McEntee, et al. (2000). "Highly unsaturated (n-3) fatty
acids, but not alpha-linolenic, conjugated linoleic or gamma-linolenic acids,
reduce tumorigenesis in Apc(Min/+) mice." J Nutr 130(10): 2434-43.
Pedersen, J. I., J. Ringstad, et al. (2000). "Adipose tissue fatty acids and
risk of myocardial infarction--a case-control study." Eur J Clin Nutr
54(8): 618-25.
Palozza, P., G. Calviello, et al. (2000). "Beta-carotene antagonizes the effects
of eicosapentaenoic acid on cell growth and lipid peroxidation in WiDr
adenocarcinoma cells." Free Radic Biol Med 28(2): 228-34.
Palakurthi, S. S., R. Fluckiger, et al. (2000). "Inhibition of translation
initiation mediates the anticancer effect of the n-3 polyunsaturated fatty acid
eicosapentaenoic acid." Cancer Res 60(11): 2919-25.
Pakala, R., W. L. Sheng, et al. (2000). "Vascular smooth muscle cells preloaded
with eicosapentaenoic acid and docosahexaenoic acid fail to respond to serotonin
stimulation." Atherosclerosis 153(1): 47-57.
Osmundsen, H. and P. Clouet (2000). "Metabolic effects of omega-3 fatty acids."
Biofactors 13(1-4): 5-8.
Onuki, Y., M. Morishita, et al. (2000). "In vivo effects of highly purified
docosahexaenoic acid on rectal insulin absorption." Int J Pharm 198(2):
147-56.
Olafsson, S. O., J. Hallgrimsson, et al. (2000). "Dietary cod liver oil
decreases arachidonic acid in rat gastric mucosa and increases stress-induced
gastric erosions." Lipids 35(6): 601-5.
Okabe, H. (2000). "[Ageing society and laboratory medicine]." Rinsho Byori
48(9): 783-96.
Oguogho, A., A. A. Aghajanian, et al. (2000). "Prostaglandin synthesis in human
lymphatics from precursor fatty acids." Lymphology 33(2): 62-6.
Ogilvie, G. K., M. J. Fettman, et al. (2000). "Effect of fish oil, arginine, and
doxorubicin chemotherapy on remission and survival time for dogs with lymphoma:
a double-blind, randomized placebo-controlled study." Cancer 88(8):
1916-28.
Oarada, M., H. Furukawa, et al. (2000). "Fish oil diet affects on oxidative
senescence of red blood cells linked to degeneration of spleen cells in mice."
Biochim Biophys Acta 1487(1): 1-14.
Nobukata, H., T. Ishikawa, et al. (2000). "Long-term administration of highly
purified eicosapentaenoic acid ethyl ester prevents diabetes and abnormalities
of blood coagulation in male WBN/Kob rats." Metabolism 49(7):
912-9.
Nobukata, H., T. Ishikawa, et al. (2000). "Long-term administration of highly
purified eicosapentaenoic acid ethyl ester improves the dysfunction of vascular
endothelial and smooth muscle cells in male WBN/Kob rats." Metabolism
49(12): 1588-91.
Nishimura, M., A. Nanbu, et al. (2000). "Eicosapentaenoic acid stimulates nitric
oxide production and decreases cardiac noradrenaline in diabetic rats." Clin
Exp Pharmacol Physiol 27(8): 618-24.
Nelson, M. M., C. F. Phleger, et al. (2000). "Lipids of gelatinous Antarctic
zooplankton: Cnidaria and Ctenophora." Lipids 35(5): 551-9.
Negretti, N., M. R. Perez, et al. (2000). "Inhibition of sarcoplasmic reticulum
function by polyunsaturated fatty acids in intact, isolated myocytes from rat
ventricular muscle." J Physiol 523 Pt 2: 367-75.
Navarro, E., M. Esteve, et al. (2000). "Abnormal fatty acid pattern in
rheumatoid arthritis. A rationale for treatment with marine and botanical
lipids." J Rheumatol 27(2): 298-303.
Nates, S. F. and C. L. McKenney, Jr. (2000). "Ontogenetic changes in biochemical
composition during larval and early postlarval development of Lepidophthalmus
louisianensis, a ghost shrimp with abbreviated development." Comp Biochem
Physiol B Biochem Mol Biol 127(4): 459-68.
Nakano, N., N. Shirasaka, et al. (2000). "C19 odd-chain polyunsaturated fatty
acids (PUfas) are metabolized to C21-PUfas in a rat liver cell line, and
curcumin, gallic acid, and their related compounds inhibit their desaturation."
Biosci Biotechnol Biochem 64(8): 1641-50.
Nakagawa, H., D. Yamamoto, et al. (2000). "Effects of genistein and synergistic
action in combination with eicosapentaenoic acid on the growth of breast cancer
cell lines." J Cancer Res Clin Oncol 126(8): 448-54.
Nagakura, T., S. Matsuda, et al. (2000). "Dietary supplementation with fish oil
rich in omega-3 polyunsaturated fatty acids in children with bronchial asthma."
Eur Respir J 16(5): 861-5.
Murray, M. J., G. Kanazi, et al. (2000). "Effects of eicosapentaenoic and
gamma-linolenic acids (dietary lipids) on pulmonary surfactant composition and
function during porcine endotoxemia." Chest 117(6): 1720-7.
Murota, S. I., M. Onodera, et al. (2000). "Regulation of angiogenesis by
controlling VEGF receptor." Ann N Y Acad Sci 902: 208-12;
discussion 212-3.
Muller-Navarra, D. C., M. T. Brett, et al. (2000). "A highly unsaturated fatty
acid predicts carbon transfer between primary producers and consumers."
Nature 403(6765): 74-7.
Mukhopadhyay, S., R. Muimo, et al. (2000). "Preferential distribution of long
chain polyunsaturated fatty acids in phospatidyl ethanolamine fraction of guinea
pig alveolar apical membranes." Prostaglandins Leukot Essent Fatty Acids
62(6): 341-8.
Morita, N., M. Tanaka, et al. (2000). "Biosynthesis of fatty acids in the
docosahexaenoic acid-producing bacterium Moritella marina strain MP-1."
Biochem Soc Trans 28(6): 943-5.
Morishita, M., M. Kajita, et al. (2000). "The dose-related hypoglycemic effects
of insulin emulsions incorporating highly purified EPA and DHA." Int J Pharm
201(2): 175-85.
Mori, T. A., V. Burke, et al. (2000). "Purified eicosapentaenoic and
docosahexaenoic acids have differential effects on serum lipids and
lipoproteins, LDL particle size, glucose, and insulin in mildly hyperlipidemic
men." Am J Clin Nutr 71(5): 1085-94.
Mori, T. A., I. B. Puddey, et al. (2000). "Effect of omega 3 fatty acids on
oxidative stress in humans: GC-MS measurement of urinary F2-isoprostane
excretion." Redox Rep 5(1): 45-6.
Mori, T. A., G. F. Watts, et al. (2000). "Differential effects of
eicosapentaenoic acid and docosahexaenoic acid on vascular reactivity of the
forearm microcirculation in hyperlipidemic, overweight men." Circulation
102(11): 1264-9.
Mohan, I. K. and U. N. Das (2000). "Effect of L-arginine-nitric oxide system on
the metabolism of essential fatty acids in chemical-induced diabetes mellitus."
Prostaglandins Leukot Essent Fatty Acids 62(1): 35-46.
Mizugaki, M., F. Ishizawa, et al. (2000). "Epigallocatechin gallate increase the
prostacyclin production of bovine aortic endothelial cells." Prostaglandins
Other Lipid Mediat 62(2): 157-64.
Minihane, A. M., S. Khan, et al. (2000). "ApoE polymorphism and fish oil
supplementation in subjects with an atherogenic lipoprotein phenotype."
Arterioscler Thromb Vasc Biol 20(8): 1990-7.
Min, Y., K. Ghebremeskel, et al. (2000). "Pregnancy reduces arachidonic and
docosahexaenoic in plasma triacylglycerols of Korean women." Int J Vitam Nutr
Res 70(2): 70-5.
Mezzano, D., K. Kosiel, et al. (2000). "Cardiovascular risk factors in
vegetarians. Normalization of hyperhomocysteinemia with vitamin B(12) and
reduction of platelet aggregation with n-3 fatty acids." Thromb Res
100(3): 153-60.
Meluzzi, A., F. Sirri, et al. (2000). "Effects of dietary vitamin E on the
quality of table eggs enriched with n-3 long-chain fatty acids." Poult Sci
79(4): 539-45.
McMurray, D. N., C. A. Jolly, et al. (2000). "Effects of dietary n-3 fatty acids
on T cell activation and T cell receptor-mediated signaling in a murine model."
J Infect Dis 182 Suppl 1: S103-7.
Mattos, R., C. R. Staples, et al. (2000). "Effects of dietary fatty acids on
reproduction in ruminants." Rev Reprod 5(1): 38-45.
Matthews, K. R., D. B. Homer, et al. (2000). "Effect of whole linseed (Linum
usitatissimum) in the diet of finishing pigs on growth performance and on the
quality and fatty acid composition of various tissues." Br J Nutr 83(6):
637-43.
Matsuo, N., K. Yamada, et al. (2000). "Inhibition by dietary tea polyphenols of
chemical mediator release from rat peritoneal exudate cells." Biosci
Biotechnol Biochem 64(7): 1437-43.
Marx, N., F. Mach, et al. (2000). "Peroxisome proliferator-activated
receptor-gamma activators inhibit IFN-gamma-induced expression of the T
cell-active CXC chemokines IP-10, Mig, and I-TAC in human endothelial cells."
J Immunol 164(12): 6503-8.
Martin-Chouly, C. A., V. Menier, et al. (2000). "Modulation of PAF production by
incorporation of arachidonic acid and eicosapentaenoic acid in phospholipids of
human leukemic monocyte-like cells THP-1." Prostaglandins Other Lipid Mediat
60(4-6): 127-35.
Martin, J. C., F. Joffre, et al. (2000). "Cyclic fatty acid monomers from heated
oil modify the activities of lipid synthesizing and oxidizing enzymes in rat
liver." J Nutr 130(6): 1524-30.
Mantzioris, E., L. G. Cleland, et al. (2000). "Biochemical effects of a diet
containing foods enriched with n-3 fatty acids." Am J Clin Nutr 72(1):
42-8.
Makrides, M. and R. A. Gibson (2000). "Long-chain polyunsaturated fatty acid
requirements during pregnancy and lactation." Am J Clin Nutr 71(1
Suppl): 307S-11S.
Lu, S. C., W. H. Wu, et al. (2000). "LDL of Taiwanese vegetarians are less
oxidizable than those of omnivores." J Nutr 130(6): 1591-6.
Louw, L. and A. Dannhauser (2000). "Keloids in rural black South Africans. Part
2: dietary fatty acid intake and total phospholipid fatty acid profile in the
blood of keloid patients." Prostaglandins Leukot Essent Fatty Acids 63(5):
247-53.
Louw, L. (2000). "Keloids in rural black South Africans. Part 3: a lipid model
for the prevention and treatment of keloid formations." Prostaglandins Leukot
Essent Fatty Acids 63(5): 255-62.
Loi, C., J. M. Chardigny, et al. (2000). "Incorporation and metabolism of trans
20:5 in endothelial cells. Effect on prostacyclin synthesis." Lipids
35(8): 911-8.
Lo, C. J., K. C. Chiu, et al. (2000). "Fish oil modulates macrophage P44/P42
mitogen-activated protein kinase activity induced by lipopolysaccharide."
JPEN J Parenter Enteral Nutr 24(3): 159-63.
Liu, Y. and D. Chen (2000). "A preliminary study on intravenous infusion of
sodium eicosapentaenoate." Drug Dev Ind Pharm 26(2): 189-91.
Leonard, A. E., E. G. Bobik, et al. (2000). "Cloning of a human cDNA encoding a
novel enzyme involved in the elongation of long-chain polyunsaturated fatty
acids." Biochem J 350 Pt 3: 765-70.
Lapillonne, A., J. C. Picaud, et al. (2000). "The use of low-EPA fish oil for
long-chain polyunsaturated fatty acid supplementation of preterm infants."
Pediatr Res 48(6): 835-41.
Kurabayashi, T., M. Okada, et al. (2000). "Eicosapentaenoic acid effect on
hyperlipidemia in menopausal Japanese women. The Niigata Epadel Study Group."
Obstet Gynecol 96(4): 521-8.
Kumar, K. V., S. M. Rao, et al. (2000). "Oxidant stress and essential fatty
acids in patients with risk and established ARDS." Clin Chim Acta 298(1-2):
111-20.
Kris-Etherton, P. M., D. S. Taylor, et al. (2000). "Polyunsaturated fatty acids
in the food chain in the United States." Am J Clin Nutr 71(1
Suppl): 179S-88S.
Kremer, J. M. (2000). "n-3 fatty acid supplements in rheumatoid arthritis."
Am J Clin Nutr 71(1 Suppl): 349S-51S.
Konya, E., H. Tsuji, et al. (2000). "Effect of ethyl icosapentate on urinary
calcium and oxalate excretion." Int J Urol 7(10): 361-5.
Kohno, M., K. Yasunari, et al. (2000). "Suppression by eicosapentaenoic acid of
oxidized low-density lipoprotein and lysophosphatidylcholine-induced migration
in cultured rat vascular smooth muscle cells." Metabolism 49(5):
560-2.
Kim, Y. K., M. Y. Hwang, et al. (2000). "Effect of arachidonic acid metabolic
inhibitors on hypoxia/reoxygenation-induced renal cell injury." Ren Fail
22(2): 143-57.
Khozin-Goldberg, I., H. Z. Yu, et al. (2000). "Triacylglycerols of the red
microalga Porphyridium cruentum can contribute to the biosynthesis of eukaryotic
galactolipids." Lipids 35(8): 881-9.
Keady, T. W., C. S. Mayne, et al. (2000). "Effects of supplementation of dairy
cattle with fish oil on silage intake, milk yield and milk composition." J
Dairy Res 67(2): 137-53.
Kang, J. X. and A. Leaf (2000). "Prevention of fatal cardiac arrhythmias by
polyunsaturated fatty acids." Am J Clin Nutr 71(1 Suppl): 202S-7S.
Joy, C. B., R. Mumby-Croft, et al. (2000). "Polyunsaturated fatty acid (fish or
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Jonzo, M. D., A. Hiol, et al. (2000). "Concentrates of DHA from fish oil by
selective esterification of cholesterol by immobilized isoforms of lipase from
Candida rugosa." Enzyme Microb Technol 27(6): 443-450.
Jiang, Z. D., S. O. Ketchum, et al. (2000). "5-Lipoxygenase-derived oxylipins
from the red alga Rhodymenia pertusa." Phytochemistry 53(1):
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Jensen, C. L., M. Maude, et al. (2000). "Effect of docosahexaenoic acid
supplementation of lactating women on the fatty acid composition of breast milk
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James, M. J., R. A. Gibson, et al. (2000). "Dietary polyunsaturated fatty acids
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Jahangiri, A., W. R. Leifert, et al. (2000). "Termination of asynchronous
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Mol Cell Biochem 206(1-2): 33-41.
Igarashi, M. and T. Miyazawa (2000). "Do conjugated eicosapentaenoic acid and
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Ide, T., H. Kobayashi, et al. (2000). "Comparative effects of perilla and fish
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Hughes, D. A. and A. C. Pinder (2000). "n-3 polyunsaturated fatty acids inhibit
the antigen-presenting function of human monocytes." Am J Clin Nutr 71(1
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Hsu, H. C., Y. T. Lee, et al. (2000). "Effect of n-3 fatty acids on the
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Higdon, J. V., J. Liu, et al. (2000). "Supplementation of postmenopausal women
with fish oil rich in eicosapentaenoic acid and docosahexaenoic acid is not
associated with greater in vivo lipid peroxidation compared with oils rich in
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Hereliuk, V. I. (2000). "[The role of arachidonic and eicosapentaenoic acid
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Heller, A. and T. Koch (2000). "[Immunonutrition with omega-3-fatty acids. Are
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Harel, M., E. Lund, et al. (2000). "Modulation of arachidonate and
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Hansen, J., S. Grimsgaard, et al. (2000). "Dietary supplementation with highly
purified eicosapentaenoic acid and docosahexaenoic acid does not influence PAI-1
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Hankenson, K. D., B. A. Watkins, et al. (2000). "Omega-3 fatty acids enhance
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Haban, P., E. Zidekova, et al. (2000). "Supplementation with long-chain n-3
fatty acids in non-insulin-dependent diabetes mellitus (NIDDM) patients leads to
the lowering of oleic acid content in serum phospholipids." Eur J Nutr
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Guo, X. and Y. Ota (2000). "Incorporation of eicosapentaenoic and
docosahexaenoic acids by a yeast (FO726A)." J Appl Microbiol 89(1):
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Guil-Guerrero, J. L., E. H. Belarbi, et al. (2000). "Eicosapentaenoic and
arachidonic acids purification from the red microalga Porphyridium cruentum."
Bioseparation 9(5): 299-306.
Grimminger, F., K. Mayer, et al. (2000). "PAF-induced synthesis of tetraenoic
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Cell Mol Physiol 278(2): L268-75.
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differ in immunocompetent cell cytokine production despite differences in cell
membrane fatty acid composition." Am J Clin Nutr 72(5): 1202-5.
Grande, J. P., H. J. Walker, et al. (2000). "Suppressive effects of fish oil on
mesangial cell proliferation in vitro and in vivo." Kidney Int 57(3):
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Ghebremeskel, K., Y. Min, et al. (2000). "Blood fatty acid composition of
pregnant and nonpregnant Korean women: red cells may act as a reservoir of
arachidonic acid and docosahexaenoic acid for utilization by the developing
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Gerber, M. J., J. D. Scali, et al. (2000). "Profiles of a healthful diet and its
relationship to biomarkers in a population sample from Mediterranean southern
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Garcia, H. S., J. A. Arcos, et al. (2000). "Synthesis of glycerides containing
n-3 fatty acids and conjugated linoleic acid by solvent-free acidolysis of fish
oil." Biotechnol Bioeng 70(5): 587-91.
Gaposchkin, D. P., R. A. Zoeller, et al. (2000). "Incorporation of
polyunsaturated fatty acids into CT-26, a transplantable murine colonic
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Fritsche, K. L., M. Anderson, et al. (2000). "Consumption of eicosapentaenoic
acid and docosahexaenoic acid impair murine interleukin-12 and interferon-gamma
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Fox, S. R., M. Hamberg, et al. (2000). "Evidence for the mitochondrial
biosynthesis of 3R-hydroxy-5Z,8Z,11Z,1 4Z-eicosatetraenoic acid in the yeast
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Fokkema, M. R., D. A. Brouwer, et al. (2000). "Short-term supplementation of
low-dose gamma-linolenic acid (GLA), alpha-linolenic acid (ALA), or GLA plus ALA
does not augment LCP omega 3 status of Dutch vegans to an appreciable extent."
Prostaglandins Leukot Essent Fatty Acids 63(5): 287-92.
Finstad, H. S., H. Dyrendal, et al. (2000). "Uptake and activation of
eicosapentaenoic acid are related to accumulation of triacylglycerol in Ramos
cells dying from apoptosis." J Lipid Res 41(4): 554-63.
Fidler, N. and B. Koletzko (2000). "The fatty acid composition of human
colostrum." Eur J Nutr 39(1): 31-7.
Fernandez, F. G., J. A. Perez, et al. (2000). "Modeling of eicosapentaenoic acid
(EPA) production from Phaeodactylum tricornutum cultures in tubular
photobioreactors. Effects of dilution rate, tube diameter, and solar
irradiance." Biotechnol Bioeng 68(2): 173-83.
Engler, M. M., S. H. Bellenger-Germain, et al. (2000). "Dietary docosahexaenoic
acid affects stearic acid desaturation in spontaneously hypertensive rats."
Lipids 35(9): 1011-5.
Engler, M. B., M. M. Engler, et al. (2000). "Mechanisms of vasorelaxation
induced by eicosapentaenoic acid (20:5n-3) in WKY rat aorta." Br J Pharmacol
131(8): 1793-9.
Duchen, K., R. Casas, et al. (2000). "Human milk polyunsaturated long-chain
fatty acids and secretory immunoglobulin A antibodies and early childhood
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Du, M., D. U. Ahn, et al. (2000). "Effects of dietary conjugated linoleic acid
and linoleic:linolenic acid ratio on polyunsaturated fatty acid status in laying
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Drieu, K., R. Vranckx, et al. (2000). "Effect of the extract of Ginkgo biloba
(EGb 761) on the circulating and cellular profiles of polyunsaturated fatty
acids: correlation with the anti-oxidant properties of the extract."
Prostaglandins Leukot Essent Fatty Acids 63(5): 293-300.
Donadio, J. V., Jr. (2000). "Use of fish oil to treat patients with
immunoglobulin a nephropathy." Am J Clin Nutr 71(1 Suppl):
373S-5S.
Denson, D. D., X. Wang, et al. (2000). "Effects of fatty acids on BK channels in
GH(3) cells." Am J Physiol Cell Physiol 279(4): C1211-9.
Cunnane, S. C. (2000). "Commentary on the workshop statement. Essentiality of
and recommended dietary intakes for Omega-6 and Omega-3 fatty acids."
Prostaglandins Leukot Essent Fatty Acids 63(3): 139-44.
Connor, W. E. (2000). "Importance of n-3 fatty acids in health and disease."
Am J Clin Nutr 71(1 Suppl): 171S-5S.
Cohen, Z., I. Khozin-Goldberg, et al. (2000). "The role of triacylglycerol as a
reservoir of polyunsaturated fatty acids for the rapid production of
chloroplastic lipids in certain microalgae." Biochem Soc Trans 28(6):
740-3.
Coffa, G. and E. M. Hill (2000). "Discovery of an 11 (R)- and 12(S)-lipoxygenase
activity in ovaries of the mussel Mytilus edulis." Lipids 35(11):
1195-204.
Chiu, L. C., J. M. Wan, et al. (2000). "Induction of apoptosis by dietary
polyunsaturated fatty acids in human leukemic cells is not associated with DNA
fragmentation." Int J Oncol 17(4): 789-96.
Calviello, G., P. Palozza, et al. (2000). "n-3 PUFA dietary supplementation
inhibits proliferation and store-operated calcium influx in thymoma cells
growing in Balb/c mice." J Lipid Res 41(2): 182-9.
Calabresi, L., D. Donati, et al. (2000). "Omacor in familial combined
hyperlipidemia: effects on lipids and low density lipoprotein subclasses."
Atherosclerosis 148(2): 387-96.
Bobrov, M. Y., V. P. Shevchenko, et al. (2000). "Hydrolysis of anandamide and
eicosapentaenoic acid ethanolamide in mouse splenocytes." Biochemistry (Mosc)
65(5): 615-9.
Blair, T. A., A. Cree, et al. (2000). "Physiological effects of a fish oil
supplement on captive juvenile tuatara (Sphenodon punctatus)." Physiol
Biochem Zool 73(2): 177-91.
Belarbi, E. H., E. Molina, et al. (2000). "A process for high yield and
scaleable recovery of high purity eicosapentaenoic acid esters from microalgae
and fish oil." Enzyme Microb Technol 26(7): 516-529.
Beaudoin, F., L. V. Michaelson, et al. (2000). "Heterologous reconstitution in
yeast of the polyunsaturated fatty acid biosynthetic pathway." Proc Natl Acad
Sci U S A 97(12): 6421-6.
Barham, J. B., M. B. Edens, et al. (2000). "Addition of eicosapentaenoic acid to
gamma-linolenic acid-supplemented diets prevents serum arachidonic acid
accumulation in humans." J Nutr 130(8): 1925-31.
Barber, M. D., D. C. McMillan, et al. (2000). "Metabolic response to feeding in
weight-losing pancreatic cancer patients and its modulation by a
fish-oil-enriched nutritional supplement." Clin Sci (Lond) 98(4):
389-99.
Balendiran, G. K., F. Schnutgen, et al. (2000). "Crystal structure and
thermodynamic analysis of human brain fatty acid-binding protein." J Biol
Chem 275(35): 27045-54.
Babcock, T., W. S. Helton, et al. (2000). "Eicosapentaenoic acid (EPA): an
antiinflammatory omega-3 fat with potential clinical applications." Nutrition
16(11-12): 1116-8.
Asset, G., A. Leroy, et al. (2000). "Effects of dietary maritime pine (Pinus
pinaster)-seed oil on high-density lipoprotein levels and in vitro cholesterol
efflux in mice expressing human apolipoprotein A-I." Br J Nutr 84(3):
353-60.
Arrol, S., M. I. Mackness, et al. (2000). "The effects of fatty acids on
apolipoprotein B secretion by human hepatoma cells (HEP G2)." Atherosclerosis
150(2): 255-64.
Amusquivar, E., F. J. Ruperez, et al. (2000). "Low arachidonic acid rather than
alpha-tocopherol is responsible for the delayed postnatal development in
offspring of rats fed fish oil instead of olive oil during pregnancy and
lactation." J Nutr 130(11): 2855-65.
Alvarez, M. J., A. Diez, et al. (2000). "Short-term modulation of lipogenesis by
macronutrients in rainbow trout (Oncorhynchus mykiss) hepatocytes." Br J Nutr
84(5): 619-28.
Almallah, Y. Z., A. El-Tahir, et al. (2000). "Distal procto-colitis and n-3
polyunsaturated fatty acids: the mechanism(s) of natural cytotoxicity
inhibition." Eur J Clin Invest 30(1): 58-65.
Almallah, Y. Z., S. W. Ewen, et al. (2000). "Distal proctocolitis and n-3
polyunsaturated fatty acids (n-3 PUFAs): the mucosal effect in situ." J Clin
Immunol 20(1): 68-76.
Alaoui El Azher, M., N. Havet, et al. (2000). "Inhibition by unsaturated fatty
acids of type II secretory phospholipase A2 synthesis in guinea-pig alveolar
macrophages evidence for the eicosanoid-independent pathway." Eur J Biochem
267(12): 3633-9.
al-Othman, A. A. (2000). "Growth and lipid metabolism responses in rats fed
different dietary fat sources." Int J Food Sci Nutr 51(3): 159-67.
al-Awadhi, A. M. and C. D. Dunn (2000). "Effects of fish-oil constituents and
plasma lipids on fibrinolysis in vitro." Br J Biomed Sci 57(4):
273-80.
Akiba, S., T. Murata, et al. (2000). "Involvement of lipoxygenase pathway in
docosapentaenoic acid-induced inhibition of platelet aggregation." Biol Pharm
Bull 23(11): 1293-7.
Abulrob, A. N., M. Mason, et al. (2000). "The effect of fatty acids and
analogues upon intracellular levels of doxorubicin in cells displaying
P-glycoprotein mediated multidrug resistance." J Drug Target 8(4):
247-56.
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EPA References 2000